Scientists in Aging Research

The questions for Week 3 (Sept 22, 2008) are:

1. Other than lifespan extension, what common feature ties together the observations about mutations in age-1 and daf-2, and the inhibition of mTOR?

2. What explanations are there for the pleiotrophic effects of age-1 mutations?

3. What scientific progress occurred after the paper published by Freidman and Johnson in 1987, that facilitated the paper published by Morris et al. in1996?

4. What role does the protein product of daf-16 play in understanding the paper by Kenyon et al.

5. How does any of the above relate to the nutritional status of an organism?

Here you may access literature to be discussed on Sep 22, 2008

Frieman and Johnson, 1988

Kenyon et al., 1993

Kimura et al., 1997

Morris et al., 1996