MATERIAL AND QUESTIONS FOR NOV 10, 2008
These are the questions for November 10, 2008
1. What was the major conclusion from the McCay paper?
2. Why did Miller use genetically heterogeneous mice for his experiments on predictors of longevity? What was his main conclusion?
3. What is a biomarker of aging? Why are biomarkers of aging highly sought?
4. What are the goals of the NIA's Intervention Testing Program (ITP)? What was a major criticism of the early results obtained, and published, by the ITP investigators?
5. What is autophagy? Why might it be beneficial?
6. What effect might rapamycin have on life span in mice?
References to review follow.
Warner 2004
(This one was on the end of last weeks questions to add for this week).
Hanson2004