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Recently posted in Laboratory of Integrative Human Physiology (LIHP)

Dr. Donald Dengel, professor of kinesiology and director of the Laboratory of Integrative Human Physiology (LIHP), is the lead author of an article published in Pediatric Blood & Cancer. The article is titled, "Signs of Early Sub-Clinical Atherosclerosis in Childhood Cancer Survivors," and it examined arterial blood vessel function in 319 childhood cancer survivors and 208 sibling controls. The results of this study demonstrated that early in life, childhood cancer survivors have changes in their arterial blood vessels that indicate an increased risk for premature atherosclerosis and cardiovascular disease.

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Dr. Donald Dengel, professor of kinesiology and director of the Laboratory of Integrative Human Physiology (LIHP) [pictured above], and Tyler Bosch, doctoral candidate [pictured below] are recipients of the Scientific Manuscript Excellence Honor: Gary A. Dudley Memorial Paper for their article "Body Composition and Bone Mineral Density of National Football League Players." Their research, published in the Journal of Strength and Conditioning Research, examined the body composition of National Football League (NFL) players before the start of their regular season. The findings are a template for future studies examining fat, lean, and bone mass in NFL players.


The Gary A. Dudley Memorial Paper is one of the highest honors the National Strength and Conditioning Association gives for scholarship and is named after one of the pioneers in modern exercise physiology research.

ACH.jpg Dr. Zan Gao, assistant professor in the School of Kinesiology and director of the Physical Activity Epidemiology Lab (PAEL), and Dr. Donald Dengel, professor of kinesiology and director of the Laboratory of Integrative Human Physiology (LIHP), are co-investigators of a recently funded Academic Health Center Seed Grant titled, "Effect of a Home-based Fitness Intervention on Cardiometabolic Risk Profile in Pediatric Patients with Acute Lymphoblastic Leukemia (ALL)." This seed grant is a pilot feasibility study to collect preliminary data for a large-scale exergaming intervention in children undergoing maintenance therapy for ALL.

MarlattK-2013.jpgKara Marlatt, a doctoral student in the School of Kinesiology, is the lead author of an article published in the Journal of Pediatrics. Marlatt is a co-author with her adviser, Dr. Donald Dengel, professor of kinesiology and director of the Laboratory of Integrative Human Physiology (LIHP).

The full citation is: Marlatt KL, Steinberger J, Dengel DR, Sinaiko A, Moran A, Chow LS, Steffen LM, Zhou X, Kelly AS: Impact of pubertal development on endothelial function and arterial elasticity. The Journal of Pediatrics 2013,163(5):1432-1436.

Dr. Donald Dengel, professor of kinesiology and director of the Laboratory of Integrative Human Physiology (LIHP), is a co-author of an article to be published in the journal of Clinical Obesity.

The article is titled, "The Relative Contributions of the Abdominal Visceral and Subcutaneous Fat Depots to Cardiometabolic Risk in Youth." The research examined the effects of abdominal fat in children on the development of cardiovascular and metabolic risk factors.

Dr. Donald Dengel, professor of kinesiology and director of the Laboratory of Integrative Human Physiology (LIHP), is a co-principal investigator on a $60,000 grant awarded from the National MPS Society. This two-year grant, "Manifestations of Cardiovascular Disease in Morquio A: Evaluation, Assessment, and Therapy", will determine if carotid artery structure and function in human patients with Morquio A syndrome is abnormal compared to healthy patients (the control group). This study is being done in conjunction with Saint Louis University and Children's Hospital of Orange County.

Dr. Donald Dengel, professor of kinesiology and director of the Laboratory of Integrative Human Physiology (LIHP), participated in an International Cardiovascular Seminar at the American Heart Association's Scientific Sessions. The seminar gave a global perspective on the future of physical education programs in the school systems. Experts from around the world spoke on the status of physical education. Dr. Dengel's talk was titled, "Physical Education Trends in the United States."

Dr. Donald Dengel, professor of kinesiology and director of the Laboratory of Integrative Human Physiology (LIHP), presented work at the American Heart Association's Scientific Sessions 2013 that shows how cancer treatment takes a toll on the hearts of child survivors.

"Research has shown childhood cancer survivors face heart and other health problems decades after treatment," said Dengel. "But researchers had not—until now—looked at the heart health effects of childhood cancer treatment while survivors are still children."

Dengel and colleagues measured artery stiffness, thickness and function in 319 U.S. boys and girls (ages 9-18) who had survived leukemia or cancerous tumors. Participants had survived 5 years or longer since their initial cancer diagnosis.

Dr. Donald Dengel, professor of kinesiology and director of the Laboratory of Integrative Human Physiology (LIHP), is a co-author of an article to be published in the journal, Molecular Genetics and Metabolism. The article entitled "Carotid Intima-Media Thickness is Increased in Patients With Treated Mucopolysaccharidoses Types I and II, and Correlates With Arterial Stiffness" examined the structure of the carotid artery in children with treated Mucopolysaccharidoses Types I and II. This rare genetic disease results in premature cardiovascular and metabolic diseases.

Donald R. Dengel, Ph.D., a professor of kinesiology and director of the Laboratory of Integrative Human Physiology, and doctoral candidate BoschT_pref.jpgTyler Bosch [pictured at right] are authors of an article to be published in the Journal of Strength and Conditioning Research. The article entitled "Body Composition and Bone Mineral Density of National Football League Players" examined body composition and bone density in over 400 professional football player.

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