Before a new drug or medical device can be made available to patients, it must go through lengthy and stringent testing through a clinical trial to make sure it's safe and effective. While these studies do carry some risk, they offer access to tomorrow's treatments right now. And the Lillehei Clinical Research Unit is there to make sure it's a safe process for participants and a smooth one for investigators.
Results tagged “Innovators at Heart”
At the University of Minnesota Medical Center today, the lung transplant waiting list is half the length it was six months ago, thanks in part to a new technology that's making more donated lungs worthy of transplantation. "For some patients, that is the difference between life and death," says U assistant professor of surgery and cardiothoracic surgeon Gabriel Loor, M.D.
Though Tom Anderson is a University of Minnesota alumnus ('80 B.S.), his most vivid memories of campus are from his childhood. That's because in the fall of 1963, Anderson spent about a month at the Variety Club Heart Hospital after having a risky open-heart surgery to repair his congenital atrial septal defect, which causes reduced oxygen in the body's blood supply and gets progressively worse. At the time, even under the skilled care of the University team that pioneered the procedure, it carried a 50-50 chance of success.
At Family Camp Weekends hosted by the University of Minnesota's Paul and Sheila Wellstone Muscular Dystrophy Center, "you'll see families just being families," says Joline Dalton, M.S., C.G.C., a U genetics counselor who helped start the wildly popular camp five years ago. "It's a place where you don't have to worry if your child can participate, because everything is geared toward MD."
Early-stage cancer patients have become one of medicine's biggest success stories, as the almost 14 million survivors in the United States would be happy to attest. But for many of them, another threat lurks in the background: heart disease. Through its integrated cardio-oncology program, the University of Minnesota has taken aim at this problem with a full-bore range of research and treatment facilities geared toward the prevention and early detection of heart disease in cancer patients, and its physicians are helping patients already diagnosed with cardiovascular problems withstand cancer treatment.
When Dorothy Busch died in 2011 at age 92, her son, Tom Busch, told his cousin that his mom was his hero. The cousin, he recalls, replied, "You know, Tom, she was a hero to many, many people." It was that sentiment that prompted Tom to set up the Dorothy M. Busch Memorial Endowed Fund to support aortic valve disease and related research at the University of Minnesota.
At the Adult Congenital and Cardiovascular Genetics Center at the University of Minnesota, Cindy Martin, M.D., works with people who were born with heart defects or inherited heart diseases and finds ways to alleviate their symptoms. But in the laboratory, she conducts research that delves deeper into what exactly in the patients' genetic makeup caused their disease. And many of her patients jump at the chance to be a part of it.
Kaye Lillehei knew she was making a good investment in 2000 when she committed $13 million to the University of Minnesota to create the Lillehei Heart Institute. So when the longtime University advocate and volunteer died in November at age 91, her family felt it was only right to make a gift to the University in her honor.
By midsummer, University of Minnesota scientists engaged in cancer and cardiovascular research will be settling into their new building across from TCF Bank Stadium. Conceived as the gateway to the University's burgeoning Biomedical Discovery District (BDD), the Cancer and Cardiovascular Research Building will not only house researchers, it will also welcome passersby inside to see firsthand the impact of the research being done throughout the BDD.
It’s taken personal tragedy, years of research, and a mysterious late-night epiphany for Marie Guion Johnson, Ph.D., to develop a promising new medical device that can detect coronary-artery blockage. Her invention, called the CADence™, is a noninvasive handheld tool that she hopes eventually will be used as a functional test for people at high risk of developing heart disease, the leading cause of death in the United States.
You could call it a long-term, heartfelt commitment. In addition to its large, ongoing research contract, Medtronic recently committed another $350,000 to the University of Minnesota’s Visible Heart® Laboratory—the only place in the world where human hearts (donated, not suitable for transplantation) are reanimated so scientists can see exactly how they work from the inside.
On September 2, 1952, a sickly Jacqueline Johnson came to the University of Minnesota Hospitals for help. Jacqueline, the 5-year-old daughter of traveling carnival workers, had an atrial septal defect that needed repair—a repair that had never been done before. But pioneering University surgeon F. John Lewis, M.D., Ph.D., took the bold move of attempting the fix.
Though he's still early in his medical career, Demetris Yannopoulos, M.D., isn't waiting to make his mark on the field of cardiology. He is considered an authority in cardiorespiratory interactions and hypothermia during CPR, and his work in has already helped to improve CPR practices—thereby saving lives of people who need it.
Experts at the University of Minnesota's Lillehei Heart Institute and the School of Public Health have developed a program to spread the word about steps Minnesotans can take to prevent a first heart attack or stroke. To start, the program will highlight the benefits of taking low-dose aspirin daily. Called "Partners in Prevention," the pilot program rolled out in Hibbing earlier this year. "Why should any Minnesotan, or American, suffer a preventable heart attack or stroke?" asks Alan T. Hirsch, M.D., director of this new initiative and the University's vascular medicine program. "This campaign is all about prevention."
In 1952, Eisenhower became president, Hasbro introduced Mr. Potato Head, gas cost 20 cents a gallon, and, at the University of Minnesota, doctors performed the world's first successful open-heart surgery. Jay Pearson was just 4 years old when he was admitted to the University's Variety Club Children's Heart Hospital on March 28, 1952, for an early heart surgery that preceded the history-making procedure by mere months.