December 26, 2012

Exam #2 Results

Exam #2 is graded and final grades have been submitted. Here are the statistics for the second exam (out of 80 points):

Mean: 60.21 (75.26%)
Median: 62 (77.5%)
Standard Deviation: 10.18 (12.73%)
Range: 41-74 (51.25-92.5%)

If you'd like to look through your second exam, please email me a time you'd like to stop by my office. Thank you for a great semester and best wishes for spring 2013.

December 12, 2012

Problem Set #4 Key

Download the key to problem set 4.

December 5, 2012

Problem Set 4 - Due 12/12/2012

Problem set #4 must be turned in by 5 pm either electronically or in my department mailbox (A14).

Download problem set 4.

Minute Papers Due 12/07/2012

Please post this week's minute papers as "comments" to this post. Minute papers should be posted by 5 pm on Friday. Feel free to read your classmate's posts.

November 29, 2012

Lecture 22 Notes

Here are the notes for Dr. Joe Dalluge's second guest lecture:

Download the powerpoint file.

Download the pdf file.

November 28, 2012

Minute Papers Due 11/30/2012

Please post this week's minute papers as "comments" to this post. Minute papers should be posted by 5 pm on Friday. Feel free to read your classmate's posts.

November 27, 2012

Lecture 21 Notes

Our guest lecturer Joe Dalluge will be discussing MS for the next two class periods. Below you will find his notes for Wednesday.

Download the powerpoint file.

Download the pdf file.

November 20, 2012

Presentation Order

12/03/12: Anciaux, DeWilde, Weisenberger

12/05/12: Egger, Kang, Schnepper

12/07/12: A. Johnson, Ramezani, Zhang

12/10/12: Gruba, Irwin, Qiu

12/12/12: F. Johnson, Ricarte

Your slides should be submitted to me via email by 5 pm the day before your presentation.

You should plan for a 12 minute presentation with an additional 5 minutes for questions from the class.

November 19, 2012

White Paper/Presentation Guidelines

Here are the details I gave in class this morning (also echoed in the syllabus):

Goal: Identify an unanswered analytical chemistry research question and choose an appropriate spectroscopic technique to explore it

Deliverables: White paper (grant overview), outline of experiments, and 12 minute presentation

Grade:
*White paper and outline - 15% (Due 11/30/12)
*Presentation - 15% (12/03, 12/05, 12/07, 12/10 or 12/12/12)

Initial step in the grant-writing process.
Single-spaced 12 point or larger font; limit document length to 2 pages including figures with minimal necessary references on additional pages (white paper) and an additional 2 pages of experimental outline.

Please address the following topics in your white paper/outline:

Background/context: emphasis area and problem to be addressed
Objective: what you plan to accomplish in a three-year program
Rationale: value to the scientific community and/or general public
Novelty: role of this research in advancing knowledge and state-of-the-art
Approach: strategy for addressing the problem
Results: anticipated output of a successful effort
Funding Request Amount: a per-year approximation of overall funding requirements

Include: sample preparation, control experiments, analysis methods

For the presentation:
12 minute in-class presentation + 5 minute Q/A period
Done on 12/03, 12/05, 12/07, 12/10 or 12/12/12
(let me know if one of these dates does NOT work for you)

White board or powerpoint
-submit copy of presentation by 5 pm on day before
Keep audience in mind
Pay special attention to correct referencing/citation


November 18, 2012

Lecture 20 Notes

After finishing the notes posted on for Friday, we will continue with these:

Download the powerpoint file.

Download the pdf file.

Sample White Paper/Experimental Outline

Here is an example of a white paper and outline from a previous class: Download file.


November 15, 2012

Lecture 19 Notes

After finishing our sub-diffraction imaging discussion, we will start on Raman:

Download the pdf file.

Download the powerpoint file.

Minute Papers Due 11/16/2012

Please post this week's minute papers as "comments" to this post. Minute papers should be posted by 5 pm on Friday. Feel free to read your classmate's posts.

November 13, 2012

Paper to Read for 11/14/2012

Please read this paper for in-class discussion on Wednesday.

A great resource on this topic is http://www.microscopyu.com/articles/superresolution/index.html.

Here are the discussion questions:
1. What is the diffraction limit and why do we want to overcome it?
2. What is a photoswitching molecule?
3. Why are they critically important for sub-diffraction fluorescence imaging?
4. How is a diffraction-limited signal converted into a sub-diffraction image?
5. Why is the emission maximum red-shifted from the absorption maximum?
6. Describe the 3 major classes of photoswitchable dyes discussed here.
7. What experiment would you pursue using sub-diffraction fluorescence imaging?

Lecture 18 Notes

Here are the lecture notes that were missing from Friday's lecture:

Download the powerpoint file.

Download the pdf file.

We will finish this set of notes and then discuss the subdiffraction resolution paper posted in a separate entry.