Lecture 22 Notes
Here are the notes for Dr. Joe Dalluge's second guest lecture:
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Here are the notes for Dr. Joe Dalluge's second guest lecture:
Please post this week's minute papers as "comments" to this post. Minute papers should be posted by 5 pm on Friday. Feel free to read your classmate's posts.
Our guest lecturer Joe Dalluge will be discussing MS for the next two class periods. Below you will find his notes for Wednesday.
12/03/12: Anciaux, DeWilde, Weisenberger
12/05/12: Egger, Kang, Schnepper
12/07/12: A. Johnson, Ramezani, Zhang
12/10/12: Gruba, Irwin, Qiu
12/12/12: F. Johnson, Ricarte
Your slides should be submitted to me via email by 5 pm the day before your presentation.
You should plan for a 12 minute presentation with an additional 5 minutes for questions from the class.
Here are the details I gave in class this morning (also echoed in the syllabus):
Goal: Identify an unanswered analytical chemistry research question and choose an appropriate spectroscopic technique to explore it
Deliverables: White paper (grant overview), outline of experiments, and 12 minute presentation
Grade:
*White paper and outline - 15% (Due 11/30/12)
*Presentation - 15% (12/03, 12/05, 12/07, 12/10 or 12/12/12)
Initial step in the grant-writing process.
Single-spaced 12 point or larger font; limit document length to 2 pages including figures with minimal necessary references on additional pages (white paper) and an additional 2 pages of experimental outline.
Please address the following topics in your white paper/outline:
Background/context: emphasis area and problem to be addressed
Objective: what you plan to accomplish in a three-year program
Rationale: value to the scientific community and/or general public
Novelty: role of this research in advancing knowledge and state-of-the-art
Approach: strategy for addressing the problem
Results: anticipated output of a successful effort
Funding Request Amount: a per-year approximation of overall funding requirements
Include: sample preparation, control experiments, analysis methods
For the presentation:
12 minute in-class presentation + 5 minute Q/A period
Done on 12/03, 12/05, 12/07, 12/10 or 12/12/12
(let me know if one of these dates does NOT work for you)
White board or powerpoint
-submit copy of presentation by 5 pm on day before
Keep audience in mind
Pay special attention to correct referencing/citation
After finishing the notes posted on for Friday, we will continue with these:
Here is an example of a white paper and outline from a previous class: Download file.
After finishing our sub-diffraction imaging discussion, we will start on Raman:
Please post this week's minute papers as "comments" to this post. Minute papers should be posted by 5 pm on Friday. Feel free to read your classmate's posts.
Please read this paper for in-class discussion on Wednesday.
A great resource on this topic is http://www.microscopyu.com/articles/superresolution/index.html.
Here are the discussion questions:
1. What is the diffraction limit and why do we want to overcome it?
2. What is a photoswitching molecule?
3. Why are they critically important for sub-diffraction fluorescence imaging?
4. How is a diffraction-limited signal converted into a sub-diffraction image?
5. Why is the emission maximum red-shifted from the absorption maximum?
6. Describe the 3 major classes of photoswitchable dyes discussed here.
7. What experiment would you pursue using sub-diffraction fluorescence imaging?
Here are the lecture notes that were missing from Friday's lecture:
We will finish this set of notes and then discuss the subdiffraction resolution paper posted in a separate entry.
Please post this week's minute papers as "comments" to this post. Minute papers should be posted by 5 pm on Friday. Feel free to read your classmate's posts.
Friday's class will be given by guest lecturer, Ben Manning. All covered material will be relevant for our second course examination.
We will continue with this set of notes when we finish Monday's notes. Please read the pre-lecture notes posted in the previous blog entry ahead of Wednesday's class meeting.
First, we'll finish UV-vis and then start with the notes below.
Problem Set #3 is due either via email or in mailbox A14 by 5 pm on 10/24/2011.