January 2013 Archives

Week 3: Jan 28- Feb 1

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Interesting article we read in class this week- "Specifying Positional Information in the Embryo: Looking beyond Morphogens" by Michel Kerszberg and Lewis Woplert

This is what I learned/ Notes on the paper:

Positional Information- is a mechanism for pattern formation that depends on morphogens and direct cell-cell interaction. An example of this is the "French Flag Model."-when a cell acquires a positional value determined by their distance from a boundary and can interpret this information.

Two conditions specify positional information: precision and robustness

Precision: the positioning of boundaries between different cell types
Robustness: reproducible distribution of morphogens, in spite of other events.

Polarity: directional information of single cell (scale different between positional information)

Some molecules mentioned:
DPP, Sonic Hedge Hog and Activin

Week 2: Jan 21-25

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Learning how to use the microscope! :)
BlennyTeleostFish 10X.jpg

human hair 10X.jpg

Pig Embryo (Slide 7).jpg

Starfistlarvae 10X.jpg

Week 1: Jan 14-18

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Recently in class we discussed some of the differences between Evolution Biology, and Developmental Biology and what each focuses on when looking at causality, genes, targets, variation, history and timescale.

The Evolutionist focuses on selection, the source of variation, trans elements, diversity and change, phylogeny and a time scale of approximately 10-10^9 years.

The Developmental Biologist focuses on the proximate mechanisms, directors of function, cis elements, universality and constancy, cell lineage, and a time scale of about 10-10^7 years.

Overall, Evolution, Ecology, and Developmental Biology are three subdivisions that all contribute to the study of Biology.

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