Review
SAN ANTONIO, Aug. 25 -- For men with newly diagnosed metastatic prostate cancer treated with androgen deprivation therapy (ADT), PSA levels at seven months seem to predict long-term survival or early failure.
Those whose PSAs fell to below 4 ng/dL while undergoing androgen deprivation therapy had about one-third the mortality risk, of men whose levels were higher, said Maha Hussain, M.D., of the University of Michigan in Ann Arbor, reporting for the Southwestern Oncology Group (SWOG).
"This is the first trial in the setting of new D2 [metastatic] prostate cancer to demonstrate unequivocally the survival advantage associated with absolute PSA value in response to androgen deprivation therapy," Dr. Hussain and colleagues wrote in the Aug. 20 issue of the Journal of Clinical Oncology.
Posted by gruwell at August 28, 2006 7:52 AM | TrackBack