You may be interested in the Big Bang Book Club it's co-sponsored by Magers & Quinn Booksellers; Secrets of the City; Center for Science, Technology and Public Policy; and Grumpy's.
They meet the fourth Tuesday of every month at Grumpy's Bar & Grill (1111 Washington Av. S. Minneapolis) from 7-9.
This month (June 23) they're reading Ghost Map: The Story of London's Most Terrifying Epidemic--and How It Changed Science, Cities, and the Modern World by Stephen Johnson.
UM TC Wilson Library (RC133.G6 J64 2006)
Here are the books they've got coming up in the near future:
July 28: My Stroke of Insight: A Brain Scientist's Personal Journey by Jill Bolte Taylor
August 25: Black Hole War: My Battle With Stephen Hawking to Make the World Safe for Quantum Mechanics by Leonard Susskind
UM TC Walter Sci/Eng Library Books (Level F) (QC174.12 .S896 2008)
September 22: 13 Things That Don't Make Sense: The Most Baffling Scientific Mysteries of Our Time by Michael Brooks
October 27: Microcosm: E. coli and the New Science of Life by Carl Zimmer
UM TC Magrath (QR82.E6 Z56 2008)
I think it sounds like an interesting list of books...