Targeted stealth liposomes for gene therapy in colorectal cancer

Dual-targeted delivery of plasmid DNA encapsulated liposomes for the treatment of metastatic colorectal cancer

Design and characterization of aptamer-amphiphiles for selective binding

Multifunctional hydrogels

Peptide-amphiphile hydrogels for tissue engineering

Targeting cells to adhesion promoting RGD peptides presented on biomimetic interfaces or 3D matrices is becoming increasingly popular for seeking variety of applications in cell-arrays, drug delivery, biocompatible coatings, etc. Success of most of these not only depends on adhesion of cells, but also on how well do the cells proliferate and grow in such surroundings. My research focuses on designing biomimetic surfaces and investigating the fate of cells after adhesion to biomimetic peptides by studying the signaling pathways that lead cells to either successfully adhere and thereby proliferate or induce apoptosis on artificial surfaces.

Characterization of cytoprotection and immunoprotection strategies for porcine islets of Langerhans using a microfluidic containment and perfusion device

Peptide functionalized block copolymers

Designing aptamers for specific targeting