The Open Mass Spectrometry Search Algorithm [OMSSA] is an efficient search engine for identifying MS/MS peptide spectra by searching libraries of known protein sequences. OMSSA scores significant hits with a probability score developed using classical hypothesis testing, the same statistical method used in BLAST. OMSSA is free and in the public domain.
OMSSA is available at http://pubchem.ncbi.nlm.nih.gov/omssa/ A research article on OMSSA is available to U Minn TC affiliates at J Proteome Res. 2004 Sep-Oct;3(5):958-64.
Posted by Kevin Messner at February 14, 2005 1:47 AM