Moxifloxacin Appears to Achieve Therapeutic Levels in the CSF of Patients with CNS Tuberculosis

Alffenaar et al report in CID a pharmacokinetic description of a combined plasma and CSF moxifloxacin concentration measurements over time in 4 patients treated for tuberculosis meningitis during steady-state conditions. This study shows that moxifloxacin easily penetrates into the CSF. For the full article see the following:

Moxi in CSF CID 2009.pdf

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