Inflammation, Coagulation Tied to Non-AIDS Deaths in HIV Cases
An increased risk of death from diseases other than AIDS has possibly been tied to a therapy designed to help HIV-positive people, according to a new study led by Jim Neaton, a University of Minnesota biostatistician in the School of Public Health.
The results, stemming from an international study published inPLoS Medicine, found that patients receiving either of two methods of antiretroviral therapy (ART) for HIV had increased risk of death from conditions such as cardiovascular complications linked to three biomarkers: high-sensitivity C-reactive protein (hsCRP), interleukin 6 (IL-6), and D-dimer.
“There is a growing body of evidence that indicates that HIV impacts a number of diseases besides AIDS-defining conditions,� Neaton said. “The data from this biomarker study support that line of thinking.�
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