Lately a lot of press has been spent on the idea of the "loner" in society. After last months shooting at Virginia Tech, a lot of people have been speculating on what makes somebody "become a loner", as well as what can be done to create an air of inclusiveness in which people can be open and honest, and not be afraid of being bullied or otherwise excluded.
There is a significant minority of the population that doesn't have a lot of the social abilities that the mainstream populace has. Autistics, specifically "high-functioning" autistics, have a tendency to feel withdrawn from society, not necessarily because of a lack of social development, but because of (possible) physical conditions which prevent them from understanding social culture and norms. Many report several people not wanting to "fit in" arguing for their own ability to stay excluded, because this is how society makes sense for them.
Is it possible that we could be forcing a minority into assimilation by trying to create an "inclusive" society? Aspies for Freedom (http://www.aspiesforfreedom.com/) seems to argue this point at times.