Intravenous N-acetylcysteine for the Treatment of Gaucher's Disease and Parkinson's Disease

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The investigators are interested in determining if the investigators are able to detect changes in brain chemistry using Magnetic Resonance Spectroscopy (MRS) in individuals with Parkinson's disease (PD), Gaucher's disease (GD), and those without these disorders when they are given the antioxidant N-acetylcysteine (NAC). This study will combine information from a medical history, a physical examination and disease rating scales with results obtained using MRS brain scans and pharmacokinetic studies from blood samples. This research will require 1 visit that will require about 4 to 5 hours of time. During this study, participants will provide their medical history, be examined and undergo a rating scale for about one hour; the brain scan and pharmacokinetic studies will require 1.5-2 hours of time; in total the study will take about 4-5 hours.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01427517

Contact: Sarah Hilbert, MS 612-624-7745 cnru@umn.edu

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This page contains a single entry by Paul Tuite published on February 14, 2012 8:56 PM.

Detecting Dopaminergic Deficits in Individuals At-risk for Parkinsonism was the previous entry in this blog.

7T MRS in Parkinson's Disease is the next entry in this blog.

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